Continuous Renal Replacement Therapy Market, By Products (Systems, Consumables & Accessories {Dialysates & Replacement Fluids, Filters, Catheters, Bloodline Sets (Tubing Sets), Blood Warmer, Anticoagulant}), By Modality (Slow Continuous Ultra Filtration, Continuous Venovenous Hemofiltration, Continuous Venovenous Hemodialysis, Continuous Venovenous Hemodiafiltration), By Age Group (Adult, Pediatrics & Neonates), By End User (Hospitals, Specialty Clinics, Ambulatory Surgical Centers) and By Region; Global Insights & Forecast (2024 – 2030)

According to Intent Market Research, the Continuous Renal Replacement Therapy (CRRT) Market is expected to grow from USD 1.5 billion in 2023-e at a CAGR of 7.8% to touch USD 2.0 billion by 2030. The CRRT market is competitive, the prominent players in the global market include Asahi Kasei Medical, B. Braun, Baxter International, Cytosorbents, Fresenius Medical Care, Infomed SA, Medtronic, Nikkiso, NIPRO, Toray Medical.

Published: February, 2024
| Report ID: HC3059
| LifeSciences & Healthcare

As per Intent Market Research, the Continuous Renal Replacement Therapy (CRRT) Market was valued at USD 1.5 billion in 2023-e and will surpass USD 2.0 billion by 2030; growing at a CAGR of 7.8% during 2024 - 2030. The market thrives due to factors such as the increasing incidence of acute kidney injury and the growing prevalence of diabetes and hypertension

CRRT devices are crucial in filtering and purifying blood when the kidneys are impaired or not functioning properly. Recent studies have highlighted a surge in critical illness and multi-organ failure, including acute kidney injury, attributed to SARS-CoV-2. This growing demand for CRRT is addressed by devices authorized under Emergency Use Authorizations (EUAs), encompassing components such as hemodialyzers/hemofilters, delivery units, bloodlines and tubing, and dialysate solutions.

The continual rise in the global intake of patients admitted to intensive/critical care units stands out as a primary driver fueling the growth of the CRRT market. Acute kidney injury, a prevalent complication among ICU patients, has become a significant global public health concern. The consistent application of this therapy significantly impacts the management of critically ill patients, particularly those with Acute Kidney Injury (AKI) stemming from severe complications such as cancer, diabetes, or cardiac surgery. The therapy, administered exclusively in the ICU, can extend for 24 hours or longer, depending on the patient's medical condition.

Notably, a substantial percentage of hospitalized patients in the UK experience AKI and 100,000 deaths each year are associated with AKI. The rising geriatric population worldwide has contributed to a surge in ICU admissions, driven by the increasing prevalence of acute and chronic health conditions that necessitate intensive care. In APAC, the number of older persons is projected to more than double, from 630 million in 2020 to about 1.3 billion by 2050, as stated by ‘United Nations Economic and Social Commission for Asia and the Pacific’. This are anticipated to drive the demand for CRRT, contributing to the expansion of the market throughout the forecast period.

Continuous Renal Replacement Therapy Market is Booming by Increasing Incidence of Acute Kidney Injury

CRRT market is influenced by the escalating incidence of AKI, driven by factors such as sepsis, cardiac surgery, and critical illnesses. This rise in AKI cases, particularly in an aging population, propels the demand for CRRT as a vital renal replacement therapy. Additionally, the market benefits from increasing clinical advantages associated with CRRT, notably the minimal risk of infection during the procedure. Technological advancements contribute to improved safety and patient outcomes, while robust clinical evidence supports CRRT's efficacy in managing critically ill patients with kidney dysfunction.

CRRT Systems for Continuous Management of AKI

In 2023, the systems segment accounted for the major market share in the CRRT market.  CRRT systems are pivotal medical devices employed in the continuous management of AKI and other renal disorders, particularly in critically ill patients within Intensive Care Units (ICUs). These systems operate continuously, ensuring a gradual and sustained removal of waste products and excess fluids from the bloodstream.

Continuous Venovenous Hemofiltration (CVVH) Segment Dominates the CRRT Market

CVVH provides a slow and continuous removal of waste products and excess fluids from the blood. Moreover, CRRT reduces the risk of rapid fluid shifts and hemodynamic instability compared to intermittent forms of dialysis.

Source: Intent Market Research Analysis

Adult Segment Accounted for The Largest Share in the CRRT Market

Adults population grappling with AKI, increasing hospitalization rates among them, and the extensive availability of CRRT systems and disposables is driving the CRRT market growth. The adult demographic represents the fastest-growing age group in both developed and developing nations, contributing significantly to the robust demand for CRRT.

North America's Region Led by the Increasing Prevalence of AKI in the Region

North America holds the dominant position in the market due to the increasing prevalence of AKI among ICU patients, robust demand for therapy-related products surpassing other regions, and the presence of a well-established healthcare infrastructure. The region's high market share is further bolstered by increasing support from regulatory bodies and the significant presence of product manufacturers. Notably, Baxter International obtained 510(k) clearance from the US Food and Drug Administration in April 2022 for its ST Set designed used for this therapy, compatible with PrisMax or Prismaflex control units.

Major Industry Players Are Enhancing their Positions by Actively Developing CRRT Platforms

The market is characterized by intense competition due to the presence of numerous international and domestic players. The continuous renal replacement therapy market, in particular, is dominated by key players such as Asahi Kasei Medical, B. Braun, Baxter International, Cytosorbents, Fresenius Medical Care, Infomed SA, Medtronic, Nikkiso, NIPRO, and Toray Medical amongst others. These industry leaders primarily focus on acquiring smaller players and innovating their product lines to cater to changing consumer preferences and needs. The success of market players is heavily dependent on their ability to adapt to changing market trends and consumer preferences.

  • In January 2023, Baxter announced a comprehensive strategic roadmap aimed at significantly elevating operational efficiency, fostering sustained long-term performance, expediting innovation, and generating enhanced value for its stakeholders. This strategic initiative encompasses the intent to establish an independent, publicly traded company by spinning off the ‘Renal Care and Acute Therapies’ global business units
  • In December 2020, Medtronic launched the Carpediem cardio-renal pediatric dialysis emergency machine in the US. This is designed for use in cases of AKI or fluid overload, catering to patients requiring hemodialysis or hemofiltration therapy

Continuous Renal Replacement Therapy Market Coverage

The report provides key insights into the continuous renal replacement therapy market, and it focuses on technological developments, trends, and initiatives taken by the government in this sector. The report delves into market drivers, restraints, and opportunities, and analyses key players and the competitive landscape within the market.

Report Scope

Report Features

Description

Market Size (2023-e)

USD 1.5 billion

Forecast Revenue (2030)

USD 2.0 billion

CAGR (2024-2030)

7.8%

Base Year for Estimation

2023-e

Historic Year

2022

Forecast Period

2024-2030

Report Coverage

Market Forecast, Market Dynamics, Competitive Landscape, Recent Developments

Segments Covered

By Product (Systems, Consumables & Accessories {Dialysates & Replacement Fluids, Filters, Catheters, Bloodline sets (tubing sets), Blood Warmer, Anticoagulant, Others}), By Modality (Slow Continuous Ultra Filtration, Continuous Venovenous Hemofiltration, Continuous Venovenous Hemodialysis, Continuous Venovenous Hemodiafiltration, Others), By Age Group (Adult, Pediatrics & Neonates), By End User (Hospitals, Specialty Clinics, Ambulatory Surgical Centers, Others)

Regional Analysis

North America (US, Canada), Europe (Germany, France, UK, Spain, Italy), Asia-Pacific (China, Japan, South Korea, India), Latin America (Brazil, Mexico, Argentina), Middle East and Africa (Saudi Arabia, South Africa, Turkey, United Arab Emirates)

Competitive Landscape

Asahi Kasei Medical, B. Braun, Baxter, Cytosorbents, Fresenius Medical Care, Infomed SA, Medtronic, Nikkiso, NIPRO, Toray Medical

Customization Scope

Customization for segments, region/country-level will be provided. Moreover, additional customization can be done based on the requirements.

Purchase Options

We have three licenses to opt for Single User License, Multi-User License (Up to 5 Users), Corporate Use License (Unlimited User and Printable PDF)

 

 

1.Introduction

1.1.Study Assumptions and Market Definition

1.2.Scope of the Study

2.Research Methodology

3.Executive Summary

4.Market Dynamics

4.1.Market Growth Drivers

4.1.1.Increasing Incidence of Acute Kidney Injury

4.1.2.Increasing Clinical Advantages

4.1.3.Growing Incidence of Sepsis

4.1.4.Growing Prevalence of Diabetes and Cardiovascular Ailments

4.2.Market Growth Restraints

4.2.1.High Risk of Bleeding Complications

4.2.2.Need for More Complex Equipment

4.3.Market Growth Opportunities

4.3.1.Rapid Technological Advancement

4.3.2.Market Expansion in Emerging Economies

4.3.3.Increasing Applications of CRRT

4.4.Pestle Analysis 

4.5.Porter’s Five Forces Analysis

5.Market Outlook

5.1. Overview (Industry Snapshot)

5.2.Technology Analysis

5.3.Supply Chain Analysis

5.4.Value Chain Analysis

5.5.Regulatory Analysis

5.6.Reimbursement Analysis

5.7.Pricing Analysis

5.8.Patent Analysis

5.9.Trade Analysis

5.10. Unmet needs in the market

5.11. Trends/Disruptions Impacting Customer's Businesses

5.12. Key Conference and Events

6.Market Segment Outlook

6.1.Segment Synopsis

6.2.By Product (Market Size & Forecast: USD Billion, 2024 – 2030)

6.2.1.Systems

6.2.2.Consumables & Accessories

6.2.2.1.  Dialysates and Replacement Fluids

6.2.2.2.  Filters

6.2.2.3.  Catheters

6.2.2.4.  Bloodline Sets (Tubing sets)

6.2.2.5.  Blood Warmer

6.2.2.6.  Anticoagulant

6.2.2.7.  Others

6.3.By Modality (Market Size & Forecast: USD Billion, 2024 – 2030)

6.3.1.Slow Continuous Ultra Filtration (SCUF)

6.3.2.Continuous Venovenous Hemofiltration (CVVH)

6.3.3.Continuous Venovenous Hemodialysis (CVVHD)

6.3.4.Continuous Venovenous Hemodiafiltration (CVVHDF)

6.3.5.Others

6.4.Age Group (Market Size & Forecast: USD Billion, 2024 – 2030)

6.4.1.Adult

6.4.2.Pediatrics

6.5.By End-use Industry (Market Size & Forecast: USD Billion, 2024 – 2030)

6.5.1.Hospitals

6.5.2.Specialty Clinics

6.5.3.Ambulatory Surgical Centers

6.5.4.Others

7.Regional Outlook

7.1.Global Market Synopsis

7.2.North America (Market Size & Forecast: USD Billion, 2024 – 2030)

7.2.1.North America Continuous Renal Replacement Therapy Market Outlook

7.2.1.1.  US CRRT Market, By Product

7.2.1.2.  US CRRT Market, By Modality

7.2.1.3.  US CRRT Market, By Age Group

7.2.1.4.  US CRRT Market, By End-use Industry

*Note: Cross-segmentation by segments for each country will be covered as shown above.

7.2.2.Canada

7.3.Europe (Market Size & Forecast: USD Billion, 2024 – 2030)

7.3.1.Europe Continuous Renal Replacement Therapy Market Outlook

7.3.2.Germany

7.3.3.UK

7.3.4.France

7.3.5.Spain

7.3.6.Italy

7.4.Asia-Pacific (Market Size & Forecast: USD Billion, 2024 – 2030)

7.4.1.Asia-Pacific Continuous Renal Replacement Therapy Market Outlook

7.4.2.China

7.4.3.India

7.4.4.Japan

7.4.5.South Korea

7.4.6.Australia

7.5.Latin America (Market Size & Forecast: USD Billion, 2024 – 2030)

7.5.1.Latin America Continuous Renal Replacement Therapy Market Outlook

7.5.2.Mexico

7.5.3.Brazil

7.6.Middle East & Africa (Market Size & Forecast: USD Billion, 2024 – 2030)

7.6.1.Middle East & Africa Continuous Renal Replacement Therapy Market Outlook

7.6.2.Saudi Arabia

7.6.3.UAE

8.Competitive Landscape

8.1.Market Share Analysis

8.2.Volume Output Analysis

8.3.Company Strategy Analysis

8.4.Competitive Matrix

9.Company Profiles

9.1.Asahi Kasei Medical

9.1.1.Company Synopsis

9.1.2.Company Financials

9.1.3.Product/Service Portfolio

9.1.4.Recent Developments

9.1.5.Analyst Perception

*Note: All the companies in section 9.1 will cover the same sub-chapters as above.

9.2.B. Braun

9.3.Baxter International

9.4.Cytosorbents

9.5.Fresenius Medical Care

9.6.Infomed SA

9.7.Medtronic

9.8.Nikkiso

9.9.NIPRO

9.10. Toray Medical

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Methodology

Intent Market Research employs a rigorous methodology to minimize residual errors by carefully defining the scope, validating findings through primary research, and consistently updating our in-house database. This dynamic approach allows us to capture ongoing market fluctuations and adapt to evolving market uncertainties.

The research factors used in our methodology vary depending on the specific market being analyzed. To begin with, we incorporate both demand and supply side information into our model to identify and address market gaps. Additionally, we also employ approaches such as Macro-Indicator Analysis, Factor Analysis, Value Chain-Based Sizing, and forecasting to further increase the accuracy of the numbers and validate the findings.

Research Approach

  • Secondary Research Approach: During the initial phase of the research process, we acquire and accumulate extensive data continuously. This data is carefully filtered and validated through a variety of secondary sources.
  • Primary Research Approach: Following the consolidation of data gathered through secondary research, we initiate a validation and verification process to verify all the market numbers and assumptions by engaging with the subject matter experts.

Data Collection, Analysis and Interpretation:

Research Methodology

Our market research methodology utilizes both top-down and bottom-up approaches to segment and estimate quantitative aspects of the market. We also employ multi-perspective analysis, examining the market from distinct viewpoints.

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